PF-05186462
Product Specifications
CAS Number
1235406-03-7
Target
Sodium Channel
Related Pathways
Membrane transporter/Ion channel
Purity
0.9937
Bioactivity
PF-05186462 (PF-05150122) is a potent, state-dependent, subtype selective Nav1.7 inhibitor with IC50 of 21 nM, no significant activity against Nav1.5.
Smiles
O(C1=C(C=C(C(F)(F)F)C=C1)C=2C=CN=NC2)C3=C(Cl)C=C(S(NC4=NN=CS4)(=O)=O)C(F)=C3
Molecular Formula
C19H10ClF4N5O3S2
Molecular Weight
531.89
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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