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PF-05186462

Product Specifications

CAS Number

1235406-03-7

Target

Sodium Channel

Related Pathways

Membrane transporter/Ion channel

Purity

0.9937

Bioactivity

PF-05186462 (PF-05150122) is a potent, state-dependent, subtype selective Nav1.7 inhibitor with IC50 of 21 nM, no significant activity against Nav1.5.

Smiles

O(C1=C(C=C(C(F)(F)F)C=C1)C=2C=CN=NC2)C3=C(Cl)C=C(S(NC4=NN=CS4)(=O)=O)C(F)=C3

Molecular Formula

C19H10ClF4N5O3S2

Molecular Weight

531.89

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

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