Masitinib mesylate
Product Specifications
CAS Number
1048007-93-7
Target
PDGFR, c-Kit, FAK, Apoptosis, FGFR, Src
Related Pathways
Apoptosis, Cytoskeletal Signaling, Tyrosine Kinase/Adaptors, Angiogenesis
Purity
>99.99%
Bioactivity
Masitinib mesylate (AB-1010 mesylate) is a selective, orally bioavailable c-Kit inhibitor with an IC50 of 200 nM for human recombinant c-Kit, and IC50 values of 540/800 nM and 510 nM for PDGFRα/β and LynB, respectively.
Smiles
CS(O)(=O)=O.CN1CCN(Cc2ccc(cc2)C(=O)Nc2ccc(C)c(Nc3nc(cs3)-c3cccnc3)c2)CC1
Molecular Formula
C29H34N6O4S2
Molecular Weight
594.75
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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