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ML318

Product Specifications

CAS Number

1610516-67-0

Target

Antibiotic

Related Pathways

Microbiology/Virology

Purity

0.9893

Bioactivity

ML318 is a biaryl nitrile PvdQ acylase inhibitor (IC50 of 20 nM for binding in the acyl-binding site) . ML318 inhibits P. aeruginosa (PAO1) with IC50 of 19 ?M. ML318 prevents pyoverdine production and limits the growth of P. aeruginosa under iron-limiting conditions.

Smiles

Fc1ccc(cc1)C(C#N)c1cccc(n1)C(F)(F)F

Molecular Formula

C14H8F4N2

Molecular Weight

280.22

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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