Danicopan
Product Specifications
CAS Number
1903768-17-1
Target
Complement System
Related Pathways
Immunology/Inflammation
Purity
0.9994
Bioactivity
Danicopan (ACH-4471) (ACH-4471) is a selective, orally active small molecule factor D inhibitor with high binding affinity to human factor D, with a Kd value of 0.54 nM. Danicopan (ACH-4471) inhibits the activity of the complement replacement pathway (APC) and may block the complement replacement pathway in paroxysmal nocturnal hemoglobinuria (PNH) and atypical hemolytic uremic syndrome (aHUS) .
Smiles
CC(=O)c1nn(CC(=O)N2C[C@H](F)C[C@H]2C(=O)Nc2cccc(Br)n2)c2ccc(cc12)-c1cnc(C)nc1
Molecular Formula
C26H23BrFN7O3
Molecular Weight
580.41
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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