SC-43
Product Specifications
CAS Number
1400989-25-4
Target
Apoptosis, Phosphatase, STAT
Related Pathways
JAK/STAT signaling, Stem Cells, Metabolism, Apoptosis
Purity
0.9926
Bioactivity
SC-43 is a potent and orally active agonist of SHP-1 (PTPN6) . SC-43 inhibits the phosphorylation of STAT3 and induces cell apoptosis, and with anti-fibrotic and anticancer effects.
Smiles
FC(F)(F)c1cc(NC(=O)Nc2cccc(Oc3ccc(cc3)C#N)c2)ccc1Cl
Molecular Formula
C21H13ClF3N3O2
Molecular Weight
431.8
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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