SC-43
Product Specifications
CAS Number
1400989-25-4
Target
Apoptosis, Phosphatase, STAT
Related Pathways
JAK/STAT signaling, Stem Cells, Metabolism, Apoptosis
Purity
0.9926
Bioactivity
SC-43 is a potent and orally active agonist of SHP-1 (PTPN6) . SC-43 inhibits the phosphorylation of STAT3 and induces cell apoptosis, and with anti-fibrotic and anticancer effects.
Smiles
FC(F)(F)c1cc(NC(=O)Nc2cccc(Oc3ccc(cc3)C#N)c2)ccc1Cl
Molecular Formula
C21H13ClF3N3O2
Molecular Weight
431.8
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
More Discoveries
Explore Other Products
Browse additional items from our catalog
NBP2-34595AF488 0.1 mL
Mouse Monoclonal Cytomegalovirus p65 Antibody (CMV100) [Alexa Fluor 488]
Sign In for Pricing
View Details 
MBS1288879-01 0.5 mg (E-Coli)
Recombinant Dictyostelium discoideum Probable cytochrome P450 518B1 (cyp518B1), partial
Sign In for Pricing
View Details MBS1288879-02 0.05 mg (Baculovirus)
Recombinant Dictyostelium discoideum Probable cytochrome P450 518B1 (cyp518B1), partial
Sign In for Pricing
View Details MBS1288879-03 0.5 mg (Yeast)
Recombinant Dictyostelium discoideum Probable cytochrome P450 518B1 (cyp518B1), partial
Sign In for Pricing
View Details MBS1288879-04 0.05 mg (Mammalian-Cell)
Recombinant Dictyostelium discoideum Probable cytochrome P450 518B1 (cyp518B1), partial
Sign In for Pricing
View Details