SC-43

Product Specifications

CAS Number

1400989-25-4

Target

Apoptosis|||Phosphatase|||STAT

Related Pathways

JAK/STAT signaling|||Stem Cells|||Metabolism|||Apoptosis

Purity

0.9926

Bioactivity

SC-43 is a potent and orally active agonist of SHP-1 (PTPN6) . SC-43 inhibits the phosphorylation of STAT3 and induces cell apoptosis, and with anti-fibrotic and anticancer effects.

Smiles

FC(F)(F)c1cc(NC(=O)Nc2cccc(Oc3ccc(cc3)C#N)c2)ccc1Cl

Molecular Formula

C21H13ClF3N3O2

Molecular Weight

431.8

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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