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IQ-3

Product Specifications

CAS Number

312538-03-7

Target

JNK

Related Pathways

MAPK

Purity

≥98%

Bioactivity

IQ3 is a selective inhibitor of JNK3 (JNK3, JNK1 and JNK2 with Kd of 66 nM, 240 nM and 290 nM, respectively) . IQ 3 inhibits NF-κB/AP1 transcriptional activity in THP1-Blue cells with IC50 of 1.4 μM, also inhibits TNF-α and IL-6 production in vitro.

Smiles

O=C(ON=C1c2ccccc2-c2nc3ccccc3nc12)c1ccco1

Molecular Formula

C20H11N3O3

Molecular Weight

341.32

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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