IQ-3
Product Specifications
CAS Number
312538-03-7
Target
JNK
Related Pathways
MAPK
Purity
?98%
Bioactivity
IQ3 is a selective inhibitor of JNK3 (JNK3, JNK1 and JNK2 with Kd of 66 nM, 240 nM and 290 nM, respectively) . IQ 3 inhibits NF-?B/AP1 transcriptional activity in THP1-Blue cells with IC50 of 1.4 ?M, also inhibits TNF-? and IL-6 production in vitro.
Smiles
O=C(ON=C1c2ccccc2-c2nc3ccccc3nc12)c1ccco1
Molecular Formula
C20H11N3O3
Molecular Weight
341.32
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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