PF-06873600
Product Specifications
CAS Number
2185857-97-8
Target
CDK
Related Pathways
Cell Cycle/Checkpoint
Purity
0.9958
Bioactivity
PF-06873600, a selective and orally bioavailable cyclin-dependent kinase (CDK) inhibitor (CDK2, CDK4, and CDK6 with Ki values of 0.09 nM, 0.13 nM, and 0.16 nM, respectively), has potential antineoplastic activity.
Smiles
C[C@@]1(O)CCC[C@H]1n1c2nc(NC3CCN(CC3)S(C)(=O)=O)ncc2cc(C(F)F)c1=O
Molecular Formula
C20H27F2N5O4S
Molecular Weight
471.52
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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