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JCN037

Product Specifications

CAS Number

2305154-31-6

Target

EGFR

Related Pathways

Tyrosine Kinase/Adaptors, Angiogenesis, JAK/STAT signaling

Purity

>99.99%

Bioactivity

JCN037 is potent, non-covalent and brain-penetrant inhibitor of EGFR (EGFR, p-wtEGFR and pEGFRvIII with IC50 of 2.49 nM, 3.95 nM, 4.48 nM , respectively) .

Smiles

Fc1c(Br)cccc1Nc1ncnc2cc3OCCOc3cc12

Molecular Formula

C16H11BrFN3O2

Molecular Weight

376.18

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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