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Borussertib

Product Specifications

CAS Number

1800070-77-2

Target

Akt

Related Pathways

Cytoskeletal Signaling, PI3K/Akt/mTOR signaling

Purity

0.99

Bioactivity

Borussertib is a first-in-class covalent-allosteric inhibitor of protein kinase Akt, with an IC50 of 0.8 nM and a Ki of 2.2 nM for Aktwt.

Smiles

C=CC(=O)Nc1ccc2[nH]c(=O)n(C3CCN(Cc4ccc(cc4)-c4nc5cc[nH]c(=O)c5cc4-c4ccccc4)CC3)c2c1

Molecular Formula

C36H32N6O3

Molecular Weight

596.68

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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