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DCLK1-IN-1

Product Specifications

CAS Number

2222635-15-4

Target

Others

Related Pathways

Others

Purity

>99.99%

Bioactivity

DCLK1-IN-1 is a selective, in vivo compatible chemical probe of the kinase domain of doublecortin-like kinase 1 (DCLK1) and a highly selective DCLK1/2 inhibitor with IC50 values ​​of 9.5/57.2 nM (DCLK1) and 31/103 nM (DCLK2) by binding and kinase assays, respectively. It has low toxicity and is used to study DCLK1 biology and determine its role in cancer.

Smiles

COc1cc(ccc1Nc1ncc2N(CC(F)(F)F)C(=O)c3ccccc3N(C)c2n1)N1CCN(C)CC1

Molecular Formula

C26H28F3N7O2

Molecular Weight

527.54

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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