DCLK1-IN-1
Product Specifications
CAS Number
2222635-15-4
Target
Others
Related Pathways
Others
Purity
>99.99%
Bioactivity
DCLK1-IN-1 is a selective, in vivo compatible chemical probe of the kinase domain of doublecortin-like kinase 1 (DCLK1) and a highly selective DCLK1/2 inhibitor with IC50 values of 9.5/57.2 nM (DCLK1) and 31/103 nM (DCLK2) by binding and kinase assays, respectively. It has low toxicity and is used to study DCLK1 biology and determine its role in cancer.
Smiles
COc1cc(ccc1Nc1ncc2N(CC(F)(F)F)C(=O)c3ccccc3N(C)c2n1)N1CCN(C)CC1
Molecular Formula
C26H28F3N7O2
Molecular Weight
527.54
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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