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Capmatinib xHCl

Product Specifications

CAS Number

1029714-89-3

Target

Apoptosis, c-Met/HGFR

Related Pathways

Tyrosine Kinase/Adaptors, Apoptosis

Purity

0.9981

Bioactivity

Capmatinib xHCl (INCB28060) is a potent, orally active, selective, and ATP competitive c-Met kinase inhibitor, potently blocking in vitro kinase activity (IC50 = 0.13 nM) as well as constitutive or HGF-stimulated activity in cells (IC50 values range from 0.3 to 1.1 nM) .

Smiles

Cl.CNC(=O)c1ccc(cc1F)-c1cnc2ncc(Cc3ccc4ncccc4c3)n2n1

Molecular Formula

C23H18ClFN6O

Molecular Weight

448.89

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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