Capmatinib xHCl
Product Specifications
CAS Number
1029714-89-3
Target
Apoptosis, c-Met/HGFR
Related Pathways
Tyrosine Kinase/Adaptors, Apoptosis
Purity
0.9981
Bioactivity
Capmatinib xHCl (INCB28060) is a potent, orally active, selective, and ATP competitive c-Met kinase inhibitor, potently blocking in vitro kinase activity (IC50 = 0.13 nM) as well as constitutive or HGF-stimulated activity in cells (IC50 values range from 0.3 to 1.1 nM) .
Smiles
Cl.CNC(=O)c1ccc(cc1F)-c1cnc2ncc(Cc3ccc4ncccc4c3)n2n1
Molecular Formula
C23H18ClFN6O
Molecular Weight
448.89
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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