J14
Product Specifications
CAS Number
1043854-13-2
Target
ROS|||Reactive Oxygen Species
Related Pathways
NF-?B|||Metabolism|||Immunology/Inflammation
Purity
0.9951
Bioactivity
J-14 is an inhibitor of reversible sulfiredoxin (IC50 : 8.1 ?M) . J14 induces oxidative stress (intracellular ROS accumulation) by inhibiting sulfiredoxin, leading to cytotoxicity and cancer cell death
Smiles
OC(=O)c1ccc(CSc2nc(cc(n2)-c2ccccc2)N2CCN(CC2)c2ccccc2Cl)cc1
Molecular Formula
C28H25ClN4O2S
Molecular Weight
517.04
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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