J14

Product Specifications

CAS Number

1043854-13-2

Target

ROS|||Reactive Oxygen Species

Related Pathways

NF-?B|||Metabolism|||Immunology/Inflammation

Purity

0.9951

Bioactivity

J-14 is an inhibitor of reversible sulfiredoxin (IC50 : 8.1 ?M) . J14 induces oxidative stress (intracellular ROS accumulation) by inhibiting sulfiredoxin, leading to cytotoxicity and cancer cell death

Smiles

OC(=O)c1ccc(CSc2nc(cc(n2)-c2ccccc2)N2CCN(CC2)c2ccccc2Cl)cc1

Molecular Formula

C28H25ClN4O2S

Molecular Weight

517.04

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

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