Antibacterial agent 229
Antibacterial agent 229 (compound 8a) is a potent antibacterial agent. Antibacterial agent 229 shows antibacterial and antifungal abilities. Antibacterial agent 229 disrupts the integrity of the bacterial membrane, intercalates into DNA. Antibacterial agent 229 inhibits topoisomerase IV with an IC50 value of 10.88 µM[1].
Product Specifications
CAS Number
3049500-54-8
UNSPSC
12352005
Target
Bacterial; Fungal; Topoisomerase
Type
Reference compound
Related Pathways
Anti-infection; Cell Cycle/DNA Damage
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/antibacterial-agent-229.html
Smiles
O=C1C(C2=CSC(N)=N2)=CN(C/C(C)=N/NC(N)=S)C3=CC(Cl)=C(F)C=C31
Molecular Formula
C16H14ClFN6OS2
Molecular Weight
424.90
References & Citations
[1]Zang ZL, et al. Synthesis and antibacterial medicinal evaluation of carbothioamido hydrazonyl thiazolylquinolone with multitargeting antimicrobial potential to combat increasingly global resistance. Eur J Med Chem. 2024 Sep 5;275:116626.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Topoisomerase
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