Epiberberine chloride
Product Specifications
CAS Number
889665-86-5
Target
Cholinesterase (ChE), Reactive Oxygen Species, Beta-Secretase, Antioxidant, AChR, BACE, ROS
Related Pathways
Neuroscience, Metabolism, Oxidation-Reduction, Immunology/Inflammation, NF-κB
Purity
0.9989
Bioactivity
Epiberberine chloride, a natural pro-berberine from Coptis chinensis Franch. is an AChE, BChE, and BACE1 inhibitor with IC50 values of 1.07, 6.03, and 8.55 μM, respectively.Epiberberine chloride has antioxidant effects and inhibits the effects of Ca9-22 and Fa2R. Epiberberine chloride has antioxidant effects, inhibits the motility of Ca9-22 and FaDu cell lines, and can be used to study hyperlipidemia, Alzheimer's disease and diabetes.
Smiles
[Cl-].COc1cc2CC[n+]3cc4c5OCOc5ccc4cc3-c2cc1OC
Molecular Formula
C20H18ClNO4
Molecular Weight
371.81
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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