Epiberberine chloride

Product Specifications

CAS Number

889665-86-5

Target

Cholinesterase (ChE) |||Reactive Oxygen Species|||Beta-Secretase|||Antioxidant|||AChR|||BACE|||ROS

Related Pathways

Neuroscience|||Metabolism|||Oxidation-Reduction|||Immunology/Inflammation|||NF-?B

Purity

0.9989

Bioactivity

Epiberberine chloride, a natural pro-berberine from Coptis chinensis Franch. is an AChE, BChE, and BACE1 inhibitor with IC50 values of 1.07, 6.03, and 8.55 ?M, respectively.Epiberberine chloride has antioxidant effects and inhibits the effects of Ca9-22 and Fa2R. Epiberberine chloride has antioxidant effects, inhibits the motility of Ca9-22 and FaDu cell lines, and can be used to study hyperlipidemia, Alzheimer's disease and diabetes.