Aminopterin sodium
Product Specifications
CAS Number
58602-66-7
Target
Others, Antifolate
Related Pathways
Others, Cell Cycle/Checkpoint
Bioactivity
Aminopterin sodium is an antineoplastic agent with immunosuppressive properties. Aminopterin works as an enzyme inhibitor by competing for the folate binding site of the enzyme dihydrofolate reductase. Its binding affinity for dihydrofolate reductase effectively blocks tetrahydrofolate synthesis.
Smiles
[Na].Nc1nc(N)c2nc(CNc3ccc(cc3)C(=O)N[C@@H](CCC(O)=O)C(O)=O)cnc2n1
Molecular Formula
C19H20N8NaO5
Molecular Weight
463.41
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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