Tepoxalin
Product Specifications
CAS Number
103475-41-8
Target
COX, Lipoxygenase
Related Pathways
Immunology/Inflammation, Neuroscience, Metabolism
Purity
0.9994
Bioactivity
Tepoxalin (RWJ 20485) is a 5-lipoxygenase inhibitor potentially for the treatment of asthma, osteoarthritis. Tepoxalin inhibits COX-1, COX-2, and 5-LOX. Tepoxalin is a potent inhibitor of sheep seminal vesicle cyclooxygenase (COX) (IC50 = 4.6 microM), rat basophilic leukemia cell (RBL-1) lysate COX (IC50 = 2.85 microM) and COX from intact RBL-1 cells (IC50 = 4.2 microM) .
Smiles
C(CC(N(C)O)=O)C1=NN(C(=C1)C2=CC=C(Cl)C=C2)C3=CC=C(OC)C=C3
Molecular Formula
C20H20ClN3O3
Molecular Weight
385.84
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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