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Tepoxalin

Product Specifications

CAS Number

103475-41-8

Target

COX|||Lipoxygenase

Related Pathways

Immunology/Inflammation|||Neuroscience|||Metabolism

Purity

0.9994

Bioactivity

Tepoxalin (RWJ 20485) is a 5-lipoxygenase inhibitor potentially for the treatment of asthma, osteoarthritis. Tepoxalin inhibits COX-1, COX-2, and 5-LOX. Tepoxalin is a potent inhibitor of sheep seminal vesicle cyclooxygenase (COX) (IC50 = 4.6 microM), rat basophilic leukemia cell (RBL-1) lysate COX (IC50 = 2.85 microM) and COX from intact RBL-1 cells (IC50 = 4.2 microM) .

Smiles

C(CC(N(C)O)=O)C1=NN(C(=C1)C2=CC=C(Cl)C=C2)C3=CC=C(OC)C=C3

Molecular Formula

C20H20ClN3O3

Molecular Weight

385.84

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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