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Voxelotor

Product Specifications

CAS Number

1446321-46-5

Target

Others

Related Pathways

Others

Purity

0.9994

Bioactivity

Voxelotor (GBT 440) is a novel hemoglobin S (HbS) polymerization inhibitor primarily used for the treatment of sickle cell disease (SCD) and a cytochrome P450 3A4 inhibitor. Voxelotor targets and covalently binds to the N-terminal valine of the HbS alpha chain, thereby stabilizing sickle cell hemoglobin (HbS) .

Smiles

CC(C)n1nccc1-c1ncccc1COc1cccc(O)c1C=O

Molecular Formula

C19H19N3O3

Molecular Weight

337.37

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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