Voxelotor
Product Specifications
CAS Number
1446321-46-5
Target
Others
Related Pathways
Others
Purity
0.9994
Bioactivity
Voxelotor (GBT 440) is a novel hemoglobin S (HbS) polymerization inhibitor primarily used for the treatment of sickle cell disease (SCD) and a cytochrome P450 3A4 inhibitor. Voxelotor targets and covalently binds to the N-terminal valine of the HbS alpha chain, thereby stabilizing sickle cell hemoglobin (HbS) .
Smiles
CC(C)n1nccc1-c1ncccc1COc1cccc(O)c1C=O
Molecular Formula
C19H19N3O3
Molecular Weight
337.37
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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