H-1152
Product Specifications
CAS Number
451462-58-1
Target
ROCK
Related Pathways
Cell Cycle/Checkpoint, Stem Cells, Cytoskeletal Signaling
Bioactivity
H-1152 is a cell membrane-permeable and selective ROCK (Rho-kinase) inhibitor (Ki=1.6 nM) that increases neurite length in neuron-rich cultures and inhibits MARCKS Ser159 phosphorylation in LPA-stimulated neuronal cells.
Smiles
S(=O)(=O)(C=1C2=C(C=CC1)C=NC=C2C)N3[C@@H](C)CNCCC3
Molecular Formula
C16H21N3O2S
Molecular Weight
319.42
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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