PF 05089771
Product Specifications
CAS Number
1235403-62-9
Target
Sodium Channel
Related Pathways
Membrane transporter/Ion channel
Purity
0.9957
Bioactivity
PF 05089771 is a Selective inhibitor of Nav1.7 (IC50 = 11 nM) that interacts with the voltage-sensor domain of domain IV. It shows a slow onset of the block that is depolarization and concentration-dependent.
Smiles
Nc1n[nH]cc1-c1cc(Cl)ccc1Oc1cc(F)c(cc1Cl)S(=O)(=O)Nc1cscn1
Molecular Formula
C18H12Cl2FN5O3S2
Molecular Weight
500.35
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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