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NDI-091143

Product Specifications

CAS Number

2375840-87-0

Target

ATP Citrate Lyase

Related Pathways

Metabolism

Purity

0.9861

Bioactivity

NDI-091143 is a potent, high-affinity human ATP-citrate lyase (ACLY) inhibitor with an IC50 of 2.1 nM (ADP-Glo assay), indirectly disrupting citrate binding via an unexpected mechanism of inhibition.

Smiles

COC(=O)c1cc(Cl)c(O)c(c1)S(=O)(=O)Nc1cc(c(F)cc1F)-c1ccccc1

Molecular Formula

C20H14ClF2NO5S

Molecular Weight

453.84

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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