NDI-091143
Product Specifications
CAS Number
2375840-87-0
Target
ATP Citrate Lyase
Related Pathways
Metabolism
Purity
0.9861
Bioactivity
NDI-091143 is a potent, high-affinity human ATP-citrate lyase (ACLY) inhibitor with an IC50 of 2.1 nM (ADP-Glo assay), indirectly disrupting citrate binding via an unexpected mechanism of inhibition.
Smiles
COC(=O)c1cc(Cl)c(O)c(c1)S(=O)(=O)Nc1cc(c(F)cc1F)-c1ccccc1
Molecular Formula
C20H14ClF2NO5S
Molecular Weight
453.84
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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