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ARS-853

Product Specifications

CAS Number

1629268-00-3

Target

Apoptosis, Ras, Raf

Related Pathways

GPCR/G Protein, MAPK, Apoptosis

Purity

0.984

Bioactivity

ARS-853 is an inhibitor of K-RASG12C (IC50 : 2.5 μM), a mutant form of K-RAS that accumulates in the active GTP-bound state in certain cancer cells

Smiles

CC1(CC1)c1cc(NCC(=O)N2CCN(CC2)C2CN(C2)C(=O)C=C)c(O)cc1Cl

Molecular Formula

C22H29ClN4O3

Molecular Weight

432.94

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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