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Ocifisertib (CFI-400945 free base)

Product Specifications

CAS Number

1338806-73-7

Target

PLK, Apoptosis

Related Pathways

Cell Cycle/Checkpoint, Apoptosis

Purity

0.9904

Bioactivity

Ocifisertib (CFI-400945 free base) is a potent, selective and orally active inhibitor of polo-like kinase 4 (PLK4; Ki value 0.26 nM; IC50 value 2.8 nM) .

Smiles

O=C1[C@]2([C@@H](C2)C=3C=C4C(=CC3)C(/C=C/C5=CC=C(CN6C[C@@H](C)O[C@@H](C)C6)C=C5)=NN4)C=7C(N1)=CC=C(OC)C7

Molecular Formula

C33H34N4O3

Molecular Weight

534.65

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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