Ocifisertib (CFI-400945 free base)
Product Specifications
CAS Number
1338806-73-7
Target
PLK, Apoptosis
Related Pathways
Cell Cycle/Checkpoint, Apoptosis
Purity
0.9904
Bioactivity
Ocifisertib (CFI-400945 free base) is a potent, selective and orally active inhibitor of polo-like kinase 4 (PLK4; Ki value 0.26 nM; IC50 value 2.8 nM) .
Smiles
O=C1[C@]2([C@@H](C2)C=3C=C4C(=CC3)C(/C=C/C5=CC=C(CN6C[C@@H](C)O[C@@H](C)C6)C=C5)=NN4)C=7C(N1)=CC=C(OC)C7
Molecular Formula
C33H34N4O3
Molecular Weight
534.65
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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