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Talarozole

Product Specifications

CAS Number

201410-53-9

Target

Retinoid Receptor, Autophagy, Cytochromes P450

Related Pathways

Metabolism, Autophagy

Purity

0.98

Bioactivity

Talarozole (R115866) is an oral systemic all-trans retinoic acid metabolism blocking agent (RAMBA) that inhibits CYP26A1 and CYP26B1 with IC50s of 5.4 and 0.46 nM, respectively, for treating acne, psoriasis, and other keratinization disorders.

Smiles

CCC(CC)C(c1ccc(Nc2nc3ccccc3s2)cc1)n1cncn1

Molecular Formula

C21H23N5S

Molecular Weight

377.51

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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