Elimusertib
Product Specifications
CAS Number
1876467-74-1
Target
ATM/ATR
Related Pathways
PI3K/Akt/mTOR signaling, DNA Damage/DNA Repair
Purity
0.9984
Bioactivity
Elimusertib (BAY-1895344) is a potent, highly selective, and orally available ATR inhibitor with an IC50 of 7 nM, demonstrating significant anti-tumor efficacy as a monotherapy and strong combination potential with targeted alpha therapy Radium-223 dichloride.
Smiles
C[C@@H]1COCCN1c1cc(-c2ccnn2C)c2ccnc(-c3cc[nH]n3)c2n1
Molecular Formula
C20H21N7O
Molecular Weight
375.43
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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