CU-CPT9b
Product Specifications
CAS Number
2162962-69-6
Target
TLR
Related Pathways
Immunology/Inflammation
Purity
0.981
Bioactivity
CU-CPT9b (TLR8-specific antagonist 1) is an antagonist of toll-like receptor 8 (TLR8; Kd = 21 nM) . It inhibits activation of NF- B induced by the TLR8 agonist R-848 in TLR8-overexpressing HEK-Blue cells with an IC50 value of 0.7 nM.
Smiles
Cc1cc(ccc1O)-c1ccnc2cc(O)ccc12
Molecular Formula
C16H13NO2
Molecular Weight
251.28
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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