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CU-CPT9b

Product Specifications

CAS Number

2162962-69-6

Target

TLR

Related Pathways

Immunology/Inflammation

Purity

0.981

Bioactivity

CU-CPT9b (TLR8-specific antagonist 1) is an antagonist of toll-like receptor 8 (TLR8; Kd = 21 nM) . It inhibits activation of NF- B induced by the TLR8 agonist R-848 in TLR8-overexpressing HEK-Blue cells with an IC50 value of 0.7 nM.

Smiles

Cc1cc(ccc1O)-c1ccnc2cc(O)ccc12

Molecular Formula

C16H13NO2

Molecular Weight

251.28

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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