THZ2
Product Specifications
CAS Number
1604810-84-5
Target
CDK
Related Pathways
Cell Cycle/Checkpoint
Purity
0.9828
Bioactivity
THZ2 (CDK7-IN-1), an analog of THZ1, is a potent and selective CDK7 inhibitor (IC50:13.9 nM), with the potential to treat Triple-negative breast cancer (TNBC) .
Smiles
CN(C)C\C=C\C(=O)Nc1cccc(c1)C(=O)Nc1cccc(Nc2ncc(Cl)c(n2)-c2c[nH]c3ccccc23)c1
Molecular Formula
C31H28ClN7O2
Molecular Weight
566.05
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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