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THZ2

Product Specifications

CAS Number

1604810-84-5

Target

CDK

Related Pathways

Cell Cycle/Checkpoint

Purity

0.9828

Bioactivity

THZ2 (CDK7-IN-1), an analog of THZ1, is a potent and selective CDK7 inhibitor (IC50:13.9 nM), with the potential to treat Triple-negative breast cancer (TNBC) .

Smiles

CN(C)C\C=C\C(=O)Nc1cccc(c1)C(=O)Nc1cccc(Nc2ncc(Cl)c(n2)-c2c[nH]c3ccccc23)c1

Molecular Formula

C31H28ClN7O2

Molecular Weight

566.05

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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