Endomorphin 2
Product Specifications
CAS Number
141801-26-5
Target
Opioid Receptor
Related Pathways
Neuroscience, Endocrinology/Hormones, GPCR/G Protein
Purity
0.9964
Bioactivity
Endomorphins-2 (EM-2) could decrease both the frequency and amplitude of the sEPSC of the motoneurons in lamina IX, which was reversed by the MOR antagonist CTOP. EM-2-IR fibers originated from primary afferent fibers form symmetric synaptic connections with motoneurons innervating skeletal muscles of the lower limbs in lamina IX of the spinal ventral horn and EM-2 might exert inhibitory effects on the activities of these motoneurons through both presynaptic and postsynaptic mechanisms.
Smiles
C(N[C@@H](CC1=CC=CC=C1)C(N[C@@H](CC2=CC=CC=C2)C(N)=O)=O)(=O)[C@H]3N(C([C@H](CC4=CC=C(O)C=C4)N)=O)CCC3
Molecular Formula
C32H37N5O5
Molecular Weight
571.67
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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