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PNU-74654

Product Specifications

CAS Number

113906-27-7

Target

Apoptosis, Wnt/beta-catenin

Related Pathways

Stem Cells, Apoptosis, Cytoskeletal Signaling

Purity

0.98

Bioactivity

PNU 74654 binds to β-catenin (Kd = 450 nM), inhibiting its interaction with the transcription factor T cell factor 4 (Tcf4) resulting in disruption of the Wnt signaling pathway.

Smiles

Cc1ccc(\C=N\NC(=O)c2ccccc2Oc2ccccc2)o1

Molecular Formula

C19H16N2O3

Molecular Weight

320.34

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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