PNU-74654
Product Specifications
CAS Number
113906-27-7
Target
Apoptosis, Wnt/beta-catenin
Related Pathways
Stem Cells, Apoptosis, Cytoskeletal Signaling
Purity
0.98
Bioactivity
PNU 74654 binds to β-catenin (Kd = 450 nM), inhibiting its interaction with the transcription factor T cell factor 4 (Tcf4) resulting in disruption of the Wnt signaling pathway.
Smiles
Cc1ccc(\C=N\NC(=O)c2ccccc2Oc2ccccc2)o1
Molecular Formula
C19H16N2O3
Molecular Weight
320.34
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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