Capsazepine
Product Specifications
CAS Number
138977-28-3
Target
Apoptosis, TRP/TRPV Channel
Related Pathways
Apoptosis, Membrane transporter/Ion channel
Purity
0.9978
Bioactivity
Capsazepine is an antagonist of TRPV1 receptor (IC50 : 562 nM) . Capsazepine blocks the painful sensation of heat caused by capsaicin (the active ingredient of chilli pepper) which activates the TRPV1 ion channel. It is therefore considered to be a capsaicin antagonist.
Smiles
Oc1cc2CCCN(Cc2cc1O)C(=S)NCCc1ccc(Cl)cc1
Molecular Formula
C19H21ClN2O2S
Molecular Weight
376.9
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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