GNE-493
Product Specifications
CAS Number
1033735-94-2
Target
MTOR, PI3K
Related Pathways
PI3K/Akt/mTOR signaling
Purity
0.98
Bioactivity
GNE-493 is potent, selective, and orally available PI3K and mTOR inhibitor with potential anticancer activity.IC50s of 3.4 nM, 12 nM, 16 nM, 16 nM and 32 nM for PI3Kα, PI3Kβ, PI3Kδ, PI3Kγ and mTOR, respectively.
Smiles
CC(C)(O)c1cc2nc(nc(N3CCOCC3)c2s1)-c1cnc(N)nc1
Molecular Formula
C17H20N6O2S
Molecular Weight
372.44
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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