JH-II-127

Product Specifications

CAS Number

1700693-08-8

Target

LRRK2

Related Pathways

Autophagy

Purity

0.9832

Bioactivity

JH-II-127 is an oral inhibitor of leucine-rich repeat kinase 2 (LRRK2), targeting WT LRRK2, G2019S LRRK2, and A2016T LRRK2 with IC50 values of 6.6 nM, 2.2 nM, and 47.7 nM, respectively.

Smiles

CNc1nc(Nc2ccc(cc2OC)C(=O)N2CCOCC2)nc2[nH]cc(Cl)c12

Molecular Formula

C19H21ClN6O3

Molecular Weight

416.86

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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