JH-II-127
Product Specifications
CAS Number
1700693-08-8
Target
LRRK2
Related Pathways
Autophagy
Purity
0.9832
Bioactivity
JH-II-127 is an oral inhibitor of leucine-rich repeat kinase 2 (LRRK2), targeting WT LRRK2, G2019S LRRK2, and A2016T LRRK2 with IC50 values of 6.6 nM, 2.2 nM, and 47.7 nM, respectively.
Smiles
CNc1nc(Nc2ccc(cc2OC)C(=O)N2CCOCC2)nc2[nH]cc(Cl)c12
Molecular Formula
C19H21ClN6O3
Molecular Weight
416.86
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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