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Navarixin

Product Specifications

CAS Number

473727-83-2

Target

CXCR

Related Pathways

Immunology/Inflammation|||GPCR/G Protein|||Autophagy

Purity

0.9951

Bioactivity

Navarixin (MK-7123) (SCH527123) is a novel, selective CXC chemokine receptor 2 (CXCR2) antagonist that inhibits neutrophil activation and modulates neutrophil trafficking in animal models, characteristics that may be beneficial in the treatment of conditions with unbalanced pulmonary neutrophilia.

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CC[C@@H](Nc1c(Nc2cccc(C(=O)N(C)C)c2O)c(=O)c1=O)c1ccc(C)o1

Molecular Formula

C21H23N3O5

Molecular Weight

397.42

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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