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HDAC8-IN-1

Product Specifications

CAS Number

1417997-93-3

Target

HDAC

Related Pathways

DNA Damage/DNA Repair, Chromatin/Epigenetic

Purity

0.9983

Bioactivity

MDK-7933 (HDAC8-IN-1) is a HDAC8 inhibitor with an IC50 of 27.2 nM in cancer cell lines. MDK-7933 shows antiproliferative effects toward several human lung cancer cell lines (A549, H1299, and CL1-5) . HDAC8-IN-1 exhibits cytotoxicity against human lung CL1-5 cells without significant cytotoxicity for normal IMR-90 cells[1].

Smiles

COc1ccc(\C=C\C(=O)NO)c(c1)-c1ccc(cc1)-c1ccccc1

Molecular Formula

C22H19NO3

Molecular Weight

345.39

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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