HDAC8-IN-1
Product Specifications
CAS Number
1417997-93-3
Target
HDAC
Related Pathways
DNA Damage/DNA Repair|||Chromatin/Epigenetic
Purity
0.9983
Bioactivity
MDK-7933 (HDAC8-IN-1) is a HDAC8 inhibitor with an IC50 of 27.2 nM in cancer cell lines. MDK-7933 shows antiproliferative effects toward several human lung cancer cell lines (A549, H1299, and CL1-5) . HDAC8-IN-1 exhibits cytotoxicity against human lung CL1-5 cells without significant cytotoxicity for normal IMR-90 cells[1].
Smiles
COc1ccc(\C=C\C(=O)NO)c(c1)-c1ccc(cc1)-c1ccccc1
Molecular Formula
C22H19NO3
Molecular Weight
345.39
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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